Applied Pharmacology

Applied Pharmacology provides the essential details that are required for a solid understanding of pharmacology: how the drugs work, why side effects occur, and how the drugs are used clinically. Drs. Stan Bardal, Jason Waechter, and Doug Martin integrate the experience of the pharmacologist and the physician for a clinical focus that ensures a complete understanding of pharmacology…in print and online. By Stan Bardal, BSc(Pharm), MBA, PhD, Department of Anaesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Division of Medical Sciences, Victoria BC, Canada; Jason Waechter, BSc, MD, FRCP(C), Department of Anaesthesiology, Pharmacology and Therapeutics, Faculty of Medicine, University of British Columbia, Victorial, BC, Canada and Doug Martin, PhD(Pharmacology), Basic Biomedial Sciences, Sanford School of Medicine, University, University of South Dakota, Vermillion, SD Table of Contents: Section I - Introduction 1 - Basic Principles and Pharmacodynamics 2 - Pharmacokinetics 3 - Autonomic Pharmacology 4 - Drug Interactions 5 - Impact of Age on Pharmacology 6 - Pharmacogenetics 7 - Toxicology 8 - Herbal Medications 9 - Drug Discovery and Evaluation 10 - Addiction and Abuse Section II - Drug Classes 11 - Cardiology ACEi, ARB, Direct renin, Na channels, Beta blockers, K blockers, CCB, Anticholinergics, Adenosine, Digoxin, Statins, Fibrates, Bile acid sequestrants, Pressors, PDE3, Nitrates, Vasodilators, Natriuretic peptides 12 - Cough, Cold, and Allergy Antitussives, Expectorants, Decongestants, H1 antagonists, Mast cell stabilizers 13 - Dermatology Retinoids, Steroids-topical, Keratolytics, Imiquimod 14 - Endocrinology Alpha-glucosidase inhibitors, Biguanides, Incretins, Insulins, Meglitinides, Sulfonylureas, Thiazolidinediones, Glucagon, Estrogens, Estrogen receptor antagonists, Aromatase inhibitors, Progestins, Hormone contraception, Oxytocin, Prostaglandins-Reproduction, Androgen antagonists, Androgens, Somatostatin Analogs, GH antagonists, ACTH, Thyroid replacement, Anti-thyroid 15  - Gastroenterology Antacids-buffers, H2 antagonists, Proton pump inhibitors, GI cytoprotectants, Prokinetics: Dopamine antagonists, Antidiarrheals, Laxatives, Cannabinoids, Pancreatic enzymes, Serotonin antagonists 16 - Hematology Heparins, Direct Xa inhibitors, Direct thrombin inhibitors, Coumarins, Salicylates, ADP blockers, Anti-platelet IIb/IIIa inhibitors, Fibrinolytics, Erythropoietins, Colony stimulating factors, B vitamins, Iron 17 - Immune Modifiers Steroids-Systemic, INTRO Monoclonal Antibodies, B Cell Biologics, T Cell Biologics, Mixed Biologics, TNF Inhibitors, Antimetabolites, Calcineurin inhibitors, Targets of Rapamycin (TOR), Activated Protein C, Glatiramer 18 - Infectious Diseases INTRO antibiotics, Penicillins, Cephalosporins, Carbapenems, Glycopeptides, Fluoroquinolones, Aminoglycosides, Lincosamides, Tetracyclines, Macrolides, Oxazolidinones, Sulphonamides, Metronidazole, INTRO anti-mycobacterials, Ethambutol, Isoniazid, Pyrazinamide, Rifamycins, CCR5 antagonists, Fusion inhibitors, Integrase inhibitors, Nucleoside reverse transcriptase inhibitors (NRTI), Non-Nucleoside reverse transcriptase inhibitors (nNRTI), Protease inhibitors, Uncoating inhibitors, Neuraminidase inhibitors, Nucleoside analogs, Azole antifungals, Echinocandins, Griseofulvin, Polyenes, Pyrimidine analogs, Terbinafine, Aminoquinolines, Anti-helminthics, Anti-protozoals 19 - Musculoskeletal System Bisphosphonates, Calcitriol, Parathyroid hormone, RANKL inhibitors, Colchicine, NSAIDs, Uricosurics, Xanthine oxidase inhibitors 20 - Neoplasia Alkylators, Anthracyclines, Antimetabolites, Bleomycins, Platinum compounds, Taxanes, Topoisomerase inhibitors, Vinca alkaloids, GnRH analogues, Angiogenesis inhibitors, Tyrosine kinase inhibitors 21 - Neurology and Neuromuscular Acetaminophen, Opioids, Alpha 2 Agonists, Anesthetics-Inhaled, Anesthetics-Intravenous, Anesthetics-Local, Baclofen, Depolarizing neuromuscular blockers, Non-depolarizing neuromuscular blockers, Nicotine, Dopamine and dopamine agonists, COMT inhibitors, Cholinesterase inhibitors, Ergot alkaloids, Triptans, Topiramate, Phenytoin, Lamotrigine, GABA analogues, Carbamazepine, Barbiturates, Valproate 22 - Ophthalmology Prostaglandins, Ophthalmic, Aptamers 23 - Psychiatry Serotonin selective reuptake inhibitors (SSRI), Tricyclic Antidepressants (TCAs), Serotonin Noradrenaline reuptake inhibitors (SNRIs), Noradrenergic and specific serotonergic antidepressants (NaSSAs), Monoamine Oxidase Inhibitors (MAOIs), Noradrenaline and Dopamine reuptake inhibitors (NDRI), Lithium, First generation antipsychotics, Second generation antipsychotics, Benzodiazepines, CNS stimulants 24 - Pulmonary Beta-2 Agonists (Bronchodilators), Anti-Cholinergics, Inhaled, Leukotriene Receptor Antagonists (LTRA), Methylxanthines, Inhaled Corticosteroids, Phosphodiesterase 5 Inhibitors, Endothelin receptor antagonists, Prostaglandins, Vascular 25 - Renal/Genitourinary Thiazide Diuretics, Loop Diuretics, Potassium-sparing Diuretics,  Carbonic Anhydrase Inhibitors, Osmotic Diuretics, Antidiuretic Hormone (Vasopressin) Analogues, Anticholinergics- Bladder, Alpha 1 Antagonists, 5-alpha reductase inhibitors