Practical Phlebology

The latest volume in the Practical Phlebology series, Deep Vein Thrombosis provides trainee and practicing physicians with the ideal illustrative guide to the etiology, diagnosis, and management of deep vein thrombosis (DVT). Based on peer-reviewed literature and quality clinical trials, the book is also an essential resource for academicians. Topics include: Epidemiology, natural history, and etiology of DVT DVT prophylaxis Diagnostic techniques Anticoagulation, thrombus removal, catheter-based interventions, and thrombolysis Inferior vena cava filters Heparin-induced thrombocytopenia Femoral endovenectomy and endoluminal recanalization   CONTENTS Natural history of acute DVT DVT and mortality Thrombus resolution DVT, valve function, and recurrence Not all DVTs are the same Etiology Etiology Vein wall injury DVT prophylaxis Risk stratification Prophylaxis guidelines References Diagnosis of acute DVT Clinical evaluation Ascending phlebography Venous duplex ultrasound Computerized tomographic venography Magnetic resonance venography D-dimer tests Anticoagulants Unfractionated heparin Low-molecular-weight heparins Fondaparinux Direct thrombin inhibitors Warfarin compounds (Vitamin K antagonists) Danaparoid References New oral anticoagulants Clinical trial development VTE prophylaxis in orthopedic patients VTE prophylaxis in medically ill patients Treatment of acute VTE Reversal of the anticoagulant effect of NOACs Management of acute DVT: Anticoagulation Initial anticoagulation Duration of anticoagulation Recurrent DVT DVT and malignancy Tailoring duration of anticoagulation Ambulation and compression Strategy of thrombus removal Background Rationale for thrombus removal Treatment options for thrombus removal Recurrent DVT Inferior vena cava filters Indications Filter types Clinical decision making Randomized trials Hemodynamic performance Decision matrix Heparin-induced thrombocytopenia Overview Clinical presentation Diagnosis Management Common femoral endovenectomy and endoluminal recanalization for chronic postthrombotic iliofemoral venous obstruction Overview Operative procedure Operative complications Clinical outcomes Perspective   Anthony J. Comerot, MD, FACS, FACC, is the director of the Jobst Vascular Institute at Toledo Hospital in Ohio and adjunct professor of surgery at the University of Michigan. He received his medical degree from Temple University School of Medicine in Philadelphia, Pennsylvania, and completed his general surgery residency at Temple University Hospital and his vascular surgery fellowship at Good Samaritan Hospital, Cincinnati, Ohio. Dr. Comerota has been a major contributor to the development of some of the newest forms of treatment for vascular disease and has been the principal investigator of seven major national trials and a co-investigator of numerous others. His research interests span a broad range of arterial and venous disorders, including the management of acute DVT, therapeutic angiogenesis, noninvasive diagnosis of vascular disease, development of new devices, new drug development, and the effects of platelet-inhibiting drugs. He has received over $5 million in research funding, including support from the National Institutes of Health (NIH), the American Heart Association, and the American Diabetes Association.